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yplP [2019-09-05 11:46:19]
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yplP [2019-09-05 11:46:19]

transcriptional activator (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|SigL]-dependent promoter)
locus
BSU_21780
pI
9.30
mw
37.05 kDa
protein length
331 aa Sequence Blast
gene length
996 bp Sequence Blast
function
required for survival at low temperatures
product
transcriptional activator (for [protein|1118A21CC581B0470EC6E7C178F2523CDCA70F93|SigL]-dependent promoter)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.5|Cold stress proteins]
  • Gene

    Coordinates
    2,294,286 2,295,281

    Phenotypes of a mutant

  • The mutant is cold-sensitive [http://www.ncbi.nlm.nih.gov/sites/entrez/16585774 PubMed]
  • The protein

    Protein family

  • [SW|Transcription factors activating transcription at SigL-dependent promoters]
  • Structure

  • [PDB|3DZD] (Aquifex aeolicus NtrC, corresponds to aa 12 ... 333 of YplP, 33% identity) [pubmed|18955063]
  • Expression and Regulation

    Operons

    genes
    [gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]-[gene|8C382ECBEE4E2911E0233E0882BEA754156B9D40|yplQ]
    description
    [Pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A896 (yplP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/896 NBRP B. subtilis, Japan]
  • GP2304 ( ''yplP''::aphA3), available in [SW|Jörg Stülke]'s lab
  • BKE21780 ([gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG
  • BKK21780 ([gene|90C747D6D6194608C2CF9566F1740A6B20966A11|yplP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAATTGGCTCCTTTTGG, downstream forward: _UP4_TAGCGATCGAAAGGAGAATG
  • References

  • 16585774,12399512,21906631,18955063